Neogi Ujjwal
Infectious Disease Unit, St. John's Research Institute, Koramangla, Bangalore-560034.
Bioinformation. 2009 Sep 30;4(3):90-1. doi: 10.6026/97320630004090.
Human Immunodeficiency Virus Type 1 (HIV-1) displays extensive genetic diversity globally that poses a serious challenge in designing suitable therapeutic measures for protective immune responses in the host. After the first detection of AIDS cases in 1986, India now has the third largest HIV epidemic in world. The HIV-1 epidemic in India is still growing with introduction of new strains/subtypes and this creates a serious problem for the clinician and basic science researchers to find the effective measures. Neighboring countries in the North and North-eastern regions play an important role in the HIV-1 pandemic. An extensive multinational collaborative research effort is needed in order to identify the risk groups and geographic locales is required to monitor HIV-1 spread in Asia and to produce a successful preventive program.
1型人类免疫缺陷病毒（HIV-1）在全球范围内呈现出广泛的基因多样性，这给设计针对宿主保护性免疫反应的合适治疗措施带来了严峻挑战。自1986年首次发现艾滋病病例以来，印度目前是全球第三大HIV疫情国家。随着新毒株/亚型的引入，印度的HIV-1疫情仍在蔓延，这给临床医生和基础科学研究人员寻找有效措施带来了严重问题。印度北部和东北部的邻国在HIV-1大流行中发挥着重要作用。为了识别风险群体和地理区域，监测HIV-1在亚洲的传播并制定成功的预防计划，需要开展广泛的跨国合作研究。
