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白细胞核素标记 99mTc-HMPAO 指南——欧洲核医学协会炎症/感染工作组

Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine.

机构信息

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

出版信息

Eur J Nucl Med Mol Imaging. 2010 Apr;37(4):842-8. doi: 10.1007/s00259-010-1394-4.

DOI:10.1007/s00259-010-1394-4
PMID:20198473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2844965/
Abstract

We describe here a protocol for labelling autologous white blood cells with (99m)Tc-HMPAO based on previously published consensus papers and guidelines. This protocol includes quality control and safety procedures and is in accordance with current European Union regulations and International Atomic Energy Agency recommendations.

摘要

我们在此描述了一种基于先前发表的共识文件和指南，用 (99m)Tc-HMPAO 标记自身白细胞的方案。该方案包括质量控制和安全程序，符合当前欧盟法规和国际原子能机构的建议。

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本文引用的文献

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Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals.当前小规模制备放射性药物的良好放射药学实践（cGRPP）指南。
Eur J Nucl Med Mol Imaging. 2010 May;37(5):1049-62. doi: 10.1007/s00259-010-1407-3.
2
Ficoll-Paque versus Lymphoprep: a comparative study of two density gradient media for therapeutic bone marrow mononuclear cell preparations.菲可-泛影葡胺与淋巴细胞分离液：两种用于治疗性骨髓单个核细胞制备的密度梯度介质的比较研究
Regen Med. 2009 Sep;4(5):689-96. doi: 10.2217/rme.09.44.
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Nuclear medicine imaging of diabetic foot infection: results of meta-analysis.糖尿病足感染的核医学成像：荟萃分析结果
Nucl Med Commun. 2006 Oct;27(10):757-64. doi: 10.1097/01.mnm.0000230065.85705.b3.
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Nuclear medicine imaging of bone infections.骨感染的核医学成像
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Fever of unknown origin, infection of subcutaneous devices, brain abscesses and endocarditis.不明原因发热、皮下装置感染、脑脓肿和心内膜炎。
Nucl Med Commun. 2006 Mar;27(3):213-22. doi: 10.1097/00006231-200603000-00003.
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Nuclear medicine imaging of inflammatory/infective disorders of the abdomen.腹部炎性/感染性疾病的核医学成像
Nucl Med Commun. 2005 Jul;26(7):657-64. doi: 10.1097/01.mnm.0000169202.68011.47.
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[Fast method of labelling leukocytes with 99mTc HM PAO].[用99mTc HM PAO标记白细胞的快速方法]
Rev Esp Med Nucl. 2002 Sep-Oct;21(5):343-8. doi: 10.1016/s0212-6982(02)72105-8.
8
Labeling of mixed leukocytes with (99m)Tc-HMPAO causes severe chromosomal aberrations in lymphocytes.用（99m）锝-六甲基丙烯胺肟标记混合白细胞会导致淋巴细胞出现严重的染色体畸变。
J Nucl Med. 2002 Feb;43(2):203-6.
9
A consensus protocol for white blood cells labelling with technetium-99m hexamethylpropylene amine oxime. International Society of Radiolabeled Blood Elements (ISORBE).用锝-99m六甲基丙烯胺肟标记白细胞的共识方案。国际放射性标记血液成分协会（ISORBE）。
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Oxido-reductive state: the major determinant for cellular retention of technetium-99m-HMPAO.氧化还原状态：锝-99m-HMPAO细胞摄取的主要决定因素。
J Nucl Med. 1996 Aug;37(8):1413-6.