头孢尼西在血清、输卵管、宫颈及阴道组织中的渗透情况。

Penetration of cefonicid into serum, salpinges, cervix and vaginal tissue.

作者信息

Goisis M, Grossi F, Soncini R, Gusmitta A

机构信息

Department of Obstetrics and Gynecology, General Hospital, Lodi Milan, Italy.

出版信息

J Chemother. 1991 Feb;3(1):28-9. doi: 10.1080/1120009x.1991.11739059.

DOI:10.1080/1120009x.1991.11739059

PMID:2019859

Abstract

Cefonicid is a new cephalosporin that, given in adequate concentrations is able to kill some pathogens such as Gram-positive cocci and many Enterobacteriaceae. In this study we have evaluated 40 patients receiving 1 g of cefonicid i.m. at various times before abdominal or vaginal hysterectomy. The results of the present study indicate that a single dose of 1 g of cefonicid given intramuscularly is useful as prophylaxis and treatment of gynecological infections.

摘要

头孢尼西是一种新型头孢菌素，在足够的浓度下能够杀灭一些病原体，如革兰氏阳性球菌和许多肠杆菌科细菌。在本研究中，我们评估了40例在腹部或阴道子宫切除术之前不同时间接受1g头孢尼西肌肉注射的患者。本研究结果表明，肌肉注射单剂量1g头孢尼西可有效预防和治疗妇科感染。