[混合性性腺发育不全合并性腺母细胞瘤]

[Mixed gonadal dysgenesis combined with gonadoblastoma].

作者信息

Batashki I, Delev P, Pancheva S, Markova D, Milchev N

出版信息

Akush Ginekol (Sofiia). 2009;48(3):51-3.

PMID:20198767

Abstract

Gonadal dysgenesis is defined by incomplete or defect forming of gonads, a result of disturbed process of migration of germ cells or and their correct organization in gonadal ridge. The combination of dysgenetic gonads and Y chromosome is a prerequisite for developing ovarian neoplasma--most frequent gonadoblastoma. We present a case of mixed gonadal dysgenesis at a patient with caryotype 46XY in combination with gonadoblastoma.

摘要

性腺发育不全的定义是性腺形成不完全或存在缺陷，这是生殖细胞迁移过程紊乱或其在性腺嵴中正确组织受到干扰的结果。发育不全的性腺与Y染色体的结合是发生卵巢肿瘤——最常见的性腺母细胞瘤的先决条件。我们报告一例核型为46XY的患者合并性腺母细胞瘤的混合型性腺发育不全病例。