Department of Pediatric Surgery, Meram Medical School of Selcuk University, Konya, Turkey.
Ren Fail. 2010 Jan;32(2):162-6. doi: 10.3109/08860220903541101.
This study aimed to determine histopathologic changes in the pelviureteral junction in children with pelviureteral junction obstruction.
Seventeen pelviureteral junction specimens obtained from children were divided into two groups: pelviureteral junction obstruction (n = 7) and control (n = 10). Wall thickness of the pelviureteral junction, tunica muscularis of the pelviureteral junction, uroepithelium thickness of the pelviureteral junction, and collagen thickness of the pelviureteral junction were evaluated in resected pelviureteral junctions in children with pelviureteral junction obstruction.
The mean wall thickness of the pelviureteral junction, mean tunica muscularis of the pelviureteral junction, and uroepithelium thickness of the pelviureteral junction were not significantly higher than those in the control group. Collagen thickness values in the pelviureteral junction obstruction group were significantly higher than those in the control group.
Our data suggest that wall thickness (tunica muscularis and uroepithelium) was not significantly increased, but collagen thickness of the ureter was increased in the pelviureteral junctions of children with pelviureteral junction obstruction.
本研究旨在确定肾盂输尿管连接部梗阻患儿肾盂输尿管连接部的组织病理学变化。
将 17 个取自儿童的肾盂输尿管连接部标本分为两组：肾盂输尿管连接部梗阻（n=7）和对照组（n=10）。评估肾盂输尿管连接部梗阻患儿切除的肾盂输尿管连接部的肾盂输尿管连接部壁厚度、肾盂输尿管连接部肌层厚度、肾盂输尿管连接部尿路上皮厚度和肾盂输尿管连接部胶原厚度。
肾盂输尿管连接部壁厚度、肾盂输尿管连接部肌层厚度和肾盂输尿管连接部尿路上皮厚度的平均值均明显高于对照组。肾盂输尿管连接部梗阻组的胶原厚度值明显高于对照组。
我们的数据表明，肾盂输尿管连接部梗阻患儿的肾盂输尿管连接部壁厚度（肌层和尿路上皮）无明显增加，但输尿管胶原厚度增加。
