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出生体重500至999克婴儿的八年随访结果:对1979年和1980年出生婴儿的持续区域研究。维多利亚婴儿协作研究小组。

Eight-year outcome in infants with birth weight of 500 to 999 grams: continuing regional study of 1979 and 1980 births. Victorian Infant Collaborative Study Group.

出版信息

J Pediatr. 1991 May;118(5):761-7. doi: 10.1016/s0022-3476(05)80044-7.

DOI:10.1016/s0022-3476(05)80044-7
PMID:2019933
Abstract

The outcome at a mean age of 8.3 years was determined for 88 of 89 surviving children with birth weights of 500 to 999 gm who were born in Victoria in 1979 and 1980; the condition of the untraced child, severely disabled at 5 years of age, was assumed to be unchanged at 8 years. Principal impairments in the children at 8 years of age were cerebral palsy 8 (9%); bilateral blindness 6 (6.7%) and poor vision in another 4 (4.5%); bilateral deafness requiring amplification 5 (5.6%); and epilepsy 2 (2.2%). The Full Scale score of the Weschler Intelligence Scales for Children--Revised was available for 77 children: 5 scores (6.5%) were less than 71 (low IQ), and 9 (11.7%) were between 71 and 85 (borderline IQ). Severe disability in 16 children (18%) was due to severe cerebral palsy, bilateral blindness, or low IQ. Mild or moderate disability was present in another 18 children (20.2%) with borderline IQ, mild or moderate cerebral palsy, poor vision, deafness, or epilepsy. Significantly more outborn children (10/18, 55.6%) than inborn children (24/71, 33.8%) were disabled. Ten children required special schooling; reading accuracy or comprehension was at least 18 months behind chronologic age in 17 (23%) of 75 children in normal school who were tested. The 2-year assessment correctly estimated the category of disability at 8 years of age in 55 (62%), overestimated it in 24 (27%), and underestimated it in 10 (11%). For the 82 children also seen at 5 years age, the category of disability at 8 years of age was correctly identified in 69 children (84%), overestimated in 4 (5%), and underestimated in 9 (11%). Change in psychologic test scores was the principal reason for reclassifying children. We conclude that the 2-yar assessment was valuable in the early identification of most of the severely disabled children, but developmental delay at 2 years of age did not always portend intellectual impairment at 8 years of age.

摘要

对1979年和1980年在维多利亚州出生的89名出生体重为500至999克的存活儿童中的88名进行了研究,确定了他们在平均年龄8.3岁时的情况;那名未追踪到的儿童在5岁时重度残疾,假设其8岁时情况未变。8岁儿童的主要损伤情况如下:脑瘫8例(9%);双眼失明6例(6.7%),另有4例视力差(4.5%);需要佩戴助听器的双耳失聪5例(5.6%);癫痫2例(2.2%)。77名儿童有韦氏儿童智力量表修订版的全量表得分:5例(6.5%)得分低于71(智商低),9例(11.7%)得分在71至85之间(边缘智商)。16名儿童(18%)重度残疾,原因是重度脑瘫、双眼失明或智商低。另有18名儿童(20.2%)有边缘智商、轻度或中度脑瘫、视力差、失聪或癫痫,存在轻度或中度残疾。与出生时即住院的儿童(24/71,33.8%)相比,出生时非住院的儿童中残疾的比例显著更高(10/18,55.6%)。10名儿童需要接受特殊教育;在接受测试的75名正常学校就读的儿童中,17名(23%)的阅读准确性或阅读理解能力比实际年龄落后至少18个月。2岁时的评估在8岁时正确估计残疾类别的有55名儿童(62%),高估的有24名(27%),低估的有10名(11%)。对于5岁时也接受检查的82名儿童,8岁时的残疾类别在69名儿童(84%)中得到正确识别,高估的有4名(5%),低估的有9名(11%)。心理测试分数的变化是儿童重新分类的主要原因。我们得出结论,2岁时的评估对于早期识别大多数重度残疾儿童很有价值,但2岁时的发育迟缓并不总是预示着8岁时存在智力损伤。

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