Department of Obstetrics, São Paulo Federal University, Sao Paulo, Brazil.
Acta Obstet Gynecol Scand. 2010 Mar;89(3):343-9. doi: 10.3109/00016340903559992.
To determine whether primiparous adolescent pregnancy is associated with increased risk of iron deficiency anemia and iron deficiency when compared with older primiparas.
Prospective cohort.
Caratinga city, Minas Gerais State, Brazil.
A total of 183 women, being 61 adolescents and 122 adults.
Five peripheral vein blood samples were collected from each participant, at 9-16 and 29-36 weeks, upon admission for delivery, within the first hour after delivery and 30-60 days post-partum. We measured hemoglobin (Hb), transferrin saturation index and ferritin.
Adolescent and adult women using chi-squared test, Student's t-test and hotelling test.
There were significant differences in Hb concentration during the various sampling periods, for the whole cohort. The prevalence of anemia (Hb < 11 g/dl) did not differ significantly between adults and adolescents. The decrease in the mean transferrin levels was more intense in adolescents than in adults, especially during the second half of pregnancy. Low ferritin levels (<12 microg/l) were more frequent in adolescents than in adults during pregnancy and throughout the study period.
Although there were no significant differences in the prevalence of iron deficiency anemia (Hb < 11 g/dl) in adolescents compared to adult women, low body iron stores and ferritin (< 12 microg/l) were significantly more frequent in adolescents.
与年长的初产妇相比，确定青少年初产妇是否与缺铁性贫血和缺铁风险增加有关。
前瞻性队列研究。
巴西米纳斯吉拉斯州卡拉廷加市。
共 183 名女性，61 名青少年和 122 名成年女性。
从每个参与者采集 5 份外周静脉血样，分别在 9-16 周、29-36 周、入院分娩时、分娩后 1 小时内和产后 30-60 天进行测量。我们测量了血红蛋白（Hb）、转铁蛋白饱和度指数和铁蛋白。
使用卡方检验、学生 t 检验和霍特林检验比较青少年和成年女性。
在整个队列中，不同采样期 Hb 浓度存在显著差异。成人和青少年的贫血患病率（Hb < 11 g/dl）无显著差异。在妊娠后半期，青少年的转铁蛋白水平下降幅度明显大于成人。妊娠期间和整个研究期间，青少年的铁蛋白水平（<12 microg/l）较成人低。
尽管青少年的缺铁性贫血患病率（Hb < 11 g/dl）与成年女性相比无显著差异，但青少年的铁储备和铁蛋白（<12 microg/l）水平较低。
