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一名青少年的原发性皮肤CD30阳性间变性大细胞淋巴瘤

Primary cutaneous CD30 positive anaplastic large cell lymphoma in an adolescent.

作者信息

Vaid Reena, Cohen Bernard

机构信息

Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

Pediatr Dermatol. 2009 Nov-Dec;26(6):721-4. doi: 10.1111/j.1525-1470.2009.01021.x.

Abstract

We present a case of a 14-year-old boy with a large ulcerated plaque on the scalp for 6 months, who was found to have primary cutaneous CD30-positive, anaplastic kinase-negative, anaplastic large cell lymphoma with post-auricular lymphadenopathy. MRI, bone marrow biopsy, and laboratory data demonstrated no other systemic involvement. He was treated with radiation and low-dose oral methotrexate, with improvement of the lesion and lymphadenopathy. Very few cases of primary cutaneous CD30-positive anaplastic large cell lymphoma in the pediatric population have been reported, and our case represents one of the first pediatric patients with local lymph node involvement.

摘要

我们报告一例14岁男孩,头皮出现一个大的溃疡性斑块6个月,经检查发现患有原发性皮肤CD30阳性、间变性激酶阴性的间变性大细胞淋巴瘤,并伴有耳后淋巴结病。MRI、骨髓活检和实验室检查数据均未显示有其他全身受累情况。他接受了放疗和低剂量口服甲氨蝶呤治疗,病变和淋巴结病均有改善。儿科人群中原发性皮肤CD30阳性间变性大细胞淋巴瘤的病例报告极少,我们的病例是首批有局部淋巴结受累的儿科患者之一。

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