Vaid Reena, Cohen Bernard
Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.
Pediatr Dermatol. 2009 Nov-Dec;26(6):721-4. doi: 10.1111/j.1525-1470.2009.01021.x.
We present a case of a 14-year-old boy with a large ulcerated plaque on the scalp for 6 months, who was found to have primary cutaneous CD30-positive, anaplastic kinase-negative, anaplastic large cell lymphoma with post-auricular lymphadenopathy. MRI, bone marrow biopsy, and laboratory data demonstrated no other systemic involvement. He was treated with radiation and low-dose oral methotrexate, with improvement of the lesion and lymphadenopathy. Very few cases of primary cutaneous CD30-positive anaplastic large cell lymphoma in the pediatric population have been reported, and our case represents one of the first pediatric patients with local lymph node involvement.
我们报告一例14岁男孩，头皮出现一个大的溃疡性斑块6个月，经检查发现患有原发性皮肤CD30阳性、间变性激酶阴性的间变性大细胞淋巴瘤，并伴有耳后淋巴结病。MRI、骨髓活检和实验室检查数据均未显示有其他全身受累情况。他接受了放疗和低剂量口服甲氨蝶呤治疗，病变和淋巴结病均有改善。儿科人群中原发性皮肤CD30阳性间变性大细胞淋巴瘤的病例报告极少，我们的病例是首批有局部淋巴结受累的儿科患者之一。
