Kuramoto Y, Iizawa O, Matsunaga J, Nakamura N, Tagami H
Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan.
Acta Derm Venereol. 1991;71(5):448-9.
We report a case of Ki-1 lymphoma that developed in a 16-year-old youth who had suffered from multicentric reticulohistiocytosis for 10 years. Over the past 3 years he had had a peculiar sclerosing lesion of the leg for which oral prednisone 5 mg daily was tried for one year, with a moderate effect. He developed a marked swelling of the inguinal lymphadenopathy on the same side as the affected leg lesion, which also developed a prominent swelling of the skin surrounding the sclerosed area. Immunohistochemical analysis of the lymph node biopsy revealed the features of Ki-1 lymphoma. This is the first case of association of multicentric reticulohistiocytosis with Ki-1 lymphoma.
我们报告一例Ki-1淋巴瘤病例，该病例发生在一名患有多中心网状组织细胞增生症10年的16岁青年身上。在过去3年里，他腿部出现一种特殊的硬化性病变，为此尝试每日口服5毫克泼尼松，持续一年，效果中等。他患侧腿部病变同侧的腹股沟淋巴结出现明显肿大，硬化区域周围的皮肤也显著肿胀。淋巴结活检的免疫组织化学分析显示出Ki-1淋巴瘤的特征。这是多中心网状组织细胞增生症与Ki-1淋巴瘤相关联的首例病例。
