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新发帕金森病患者的日常生活活动和生活质量,根据疾病亚型,并与健康对照组进行比较。

Activities of daily living and quality of life in persons with newly diagnosed Parkinson's disease according to subtype of disease, and in comparison to healthy controls.

机构信息

Department of Community Medicine and Rehabilitation, Section of Occupational Therapy, Umeå University, Umeå, Sweden.

出版信息

Acta Neurol Scand. 2011 Jan;123(1):20-7. doi: 10.1111/j.1600-0404.2010.01344.x.

Abstract

OBJECTIVE

To describe activity of daily living (ADL) and quality of life (QoL) at first visit to a neurological centre, in patients subsequently diagnosed with Parkinson's disease (PD), according to subtype of disease and compared to healthy controls.

MATERIALS AND METHODS

99 patients and 31 controls were included. Patients were classified into three groups according to predominant symptoms: 50 Postural instability-gait difficulties (PIGD), 37 tremor dominant, 12 indeterminate. Evaluations included ADL-taxonomy, SF-36, and the Parkinson disease questionnaire (PDQ-39).

RESULTS

Patients experienced early on limitations in ADL and QoL compared to controls. Patients with PIGD subtype had already at first visit a worse status, clinically and in ADL and QoL, than patients with tremor dominant type.

CONCLUSIONS

Already at first visit to a neurological centre, patients who will eventually receive the diagnosis of PD exhibited restrictions in ADL and QoL. Patients with axial symptoms were affected most.

摘要

目的

描述首次就诊于神经科中心的、随后被诊断为帕金森病(PD)患者的日常生活活动(ADL)和生活质量(QoL),根据疾病亚型进行分类,并与健康对照组进行比较。

材料与方法

共纳入 99 例患者和 31 例对照组。根据主要症状将患者分为三组:50 例姿势不稳-步态困难(PIGD)、37 例震颤为主、12 例不明确。评估包括 ADL-分类、SF-36 和帕金森病问卷(PDQ-39)。

结果

与对照组相比,患者在早期就出现了 ADL 和 QoL 的受限。PIGD 亚型患者在首次就诊时,在临床、ADL 和 QoL 方面的状况就比震颤为主型患者差。

结论

即使在首次就诊于神经科中心时,最终被诊断为 PD 的患者已经表现出 ADL 和 QoL 的受限。有轴性症状的患者受影响最大。

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