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低血钾性周期性瘫痪:病例系列、文献复习及治疗更新。

Hypokalemic periodic paralysis: a case series, review of the literature and update of management.

机构信息

Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, UAE.

出版信息

Eur J Emerg Med. 2010 Feb;17(1):45-7. doi: 10.1097/mej.0b013e32832d6436.

DOI:10.1097/mej.0b013e32832d6436
PMID:20201128
Abstract

The objective of this study was to present a case series of patients with hypokalemic periodic paralysis. We described all patients with diagnosis of hypokalemic periodic paralysis admitted to the Al Ain Hospital (UAE) during the year 2006. Seventeen patients, all males and mostly Asians, were presented to the Al Ain Hospital over a 12-month period. The majority were admitted during the summer months. Four were thyrotoxic. All of the 17 patients received oral potassium supplements and recovered well without any major complications. In conclusion, clinicians should have a high index of suspicion, especially among Asians presenting with flaccid paralysis and hypokalemia. The main steps in the management include exclusion of other causes of hypokalemia, potassium replacement, hydration and close monitoring of the cardiac rhythm and serum potassium levels. When possible, the underlying cause must be adequately addressed to prevent the persistence or recurrence of paralysis.

摘要

本研究旨在报告一系列低钾周期性麻痹患者的病例。我们描述了 2006 年期间在阿联酋艾因医院(Al Ain Hospital)就诊的所有低钾周期性麻痹诊断患者。17 例患者均为男性,大多数为亚洲人,在 12 个月期间被收入 Al Ain 医院。大多数患者在夏季住院。4 例为甲状腺毒症。17 例患者均接受口服钾补充治疗,无任何严重并发症且恢复良好。总之,临床医生应保持高度怀疑,尤其是在出现弛缓性瘫痪和低钾血症的亚洲患者中。管理的主要步骤包括排除其他低钾血症的原因、补钾、补液以及密切监测心律失常和血清钾水平。在可能的情况下,必须充分解决潜在病因,以防止瘫痪持续或复发。

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