Brandenburg V M, Knackstedt C, Gobbelé R, Graf J, Schröder J, Westerhuis R, Kosinski C M
Medizinische Klinik II, Universitätsklinikum Aachen, Aachen.
Nervenarzt. 2004 Oct;75(10):1007-11. doi: 10.1007/s00115-004-1707-6.
Hypokalemic periodic paralysis as a complication of thyrotoxicosis (thyrotoxic periodic paralysis) most often occurs in east Asian men. It is characterised by recurrent episodes of flaccid paralysis, hypokalemia, and underlying hyperthyroidism. It needs to be distinguished from sporadic and familial forms of periodic hypokalemic paralysis. No disturbances in the acid-base state and no extracorporal potassium loss are present. We report on the typical case of a young Chinese man presenting with hypokalemic periodic paralysis associated with yet unknown Graves' disease. Intravenous substitution of potassium and oral propranolol were administered. Complete remission was achieved after 10 hours. After medical therapy had normalised thyroid hormone levels, no further hypokalemic paralytic attacks occurred.
低钾性周期性麻痹作为甲状腺毒症的一种并发症(甲状腺毒性周期性麻痹),最常发生于东亚男性。其特征为反复发作的弛缓性麻痹、低钾血症以及潜在的甲状腺功能亢进。它需要与散发性和家族性周期性低钾性麻痹相鉴别。不存在酸碱状态紊乱和体外钾丢失。我们报告了一名年轻中国男性的典型病例,该患者表现为与尚未明确的格雷夫斯病相关的低钾性周期性麻痹。给予了静脉补钾和口服普萘洛尔治疗。10小时后完全缓解。在药物治疗使甲状腺激素水平恢复正常后,未再发生低钾性麻痹发作。