Shimazaki C, Oku N, Gotoh H, Inaba T, Murakami S, Oku N, Itoh K, Nakanishi S, Nakagawa M, Fujita N
Second Department of Medicine, Kyoto Prefectural University of Medicine.
Rinsho Ketsueki. 1991 Jan;32(1):71-2.
A 25-year-old woman was diagnosed as acute myeloblastic leukemia (M1 in FAB classification) in May 1983, and treated with DCMP regimen, which led to the complete remission. Intensification therapies and maintenance therapy with OK-432 were continued until August 1988, and 10 months later she conceived. She delivered a healthy 2,680 g male baby at 36th week of pregnancy by Cesarean section because of abruptio placentae. This case suggests that normal pregnancy is possible in patients with acute leukemia who received anti-cancer drugs.
一名25岁女性于1983年5月被诊断为急性髓细胞白血病(FAB分类为M1),接受DCMP方案治疗后完全缓解。强化治疗及使用OK-432的维持治疗持续至1988年8月,10个月后她怀孕。因胎盘早剥,她于妊娠36周行剖宫产,分娩出一名健康的2680克男婴。该病例提示,接受过抗癌药物治疗的急性白血病患者有可能正常妊娠。