Miftode Egidia, Leca Daniela, Luca V
Facultatea de Medicină, Disciplina de Boli Infecţioase, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2008 Jul-Sep;112(3):652-5.
We report a case of rash probably induced by ciprofloxacin and/or salazopyrin administration in a patient with infectious mononucleosis. A 22 year woman developed a maculopapular and petechial eruption in the 3-rd day of ciprofloxacin (given for a genital tract infection) and the 32-nd day of salazopyrin (for a spondylodiscitis). Subsequently she developed a severe hepatitis, shock, and very severe leucocytosis (88 000/mmc) that occasioned haematological investigations for a lymphoproliferative syndrome.
我们报告一例可能由环丙沙星和/或柳氮磺胺吡啶诱发皮疹的传染性单核细胞增多症患者。一名22岁女性在使用环丙沙星(用于治疗生殖道感染)第3天和柳氮磺胺吡啶(用于治疗脊椎间盘炎)第32天时出现了斑丘疹和瘀点疹。随后她发展为严重肝炎、休克以及非常严重的白细胞增多症(88000/mmc),这引发了针对淋巴增生性综合征的血液学检查。