[Physiological and environmental factors affecting biological monitoring of exposure to organic solvent vapors].

A review of the literature was made on the physiological and environmental factors affecting pharmacokinetic behavior of organic solvent vapors in relation to biological monitoring of exposure to organic solvents. Among the physiological factors the importance is attached to body build (body weight and body fat content), sex, and physical activity. Environmental factors are centered on cigarette smoking, medications, coexistence of other solvents, dietary intake, and ethanol consumption with special emphasis of their effects on the hepatic metabolism of organic solvents.