[特异性免疫反应在慢性腹泻型乳糜泻诊断中的应用]
[Specific immune response in diagnosis of celiac disease with chronic diarrhea].
作者信息
Gudkova R B, Krums L M, Potapova V B, Sabel'nikova E A, Chikunova B Z, Parfenov A I
出版信息
Eksp Klin Gastroenterol. 2009(5):47-52.
PMID:20201304
Abstract
High concentration of Ab Gl, Ab tTG, Ab Em and Ab Rt and increased amount of immunocompetent cells in the SIM in coeliac disease is an index of the developing specific immune response to gliadin and tissue antigens. High specificity and sensitivity of Ab tTG and Ab Em were determined in celiac disease.
摘要
乳糜泻患者中，高浓度的抗麦醇溶蛋白抗体（Ab Gl）、抗组织转谷氨酰胺酶抗体（Ab tTG）、抗肌内膜抗体（Ab Em）和抗网硬蛋白抗体（Ab Rt）以及小肠黏膜固有层中免疫活性细胞数量的增加是对麦醇溶蛋白和组织抗原产生特异性免疫反应的指标。在乳糜泻中确定了抗组织转谷氨酰胺酶抗体和抗肌内膜抗体具有高特异性和敏感性。
Zotero 插件