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[英加韦林抗乙型流感病毒疗效的体外研究]

[In vitro investigation of Ingavirin efficacy against influenza B virus].

作者信息

Loginova S Ia, Borisevich S V, Semenova I A, Borisevich G V, Maksimov V A, Bondarev V P, Nebol'sin V E

出版信息

Antibiot Khimioter. 2009;54(7-8):13-5.

PMID:20201397
Abstract

The experimental investigation of Ingavirin activity against influenza B virus showed that in concentrations 100 and 200 mcg/ml it was efficient in inhibition of the virus reproduction: the cytopathic effect was lowered by 75%, the level of the pathogen accumulation in the MDCK cell culture was decreased by more than 2.0 lg and the formation of the virus specific hemagglutinin was inhibited by more than 90%.

摘要

对英加韦林抗乙型流感病毒活性的实验研究表明,在浓度为100和200微克/毫升时,它能有效抑制病毒繁殖:细胞病变效应降低75%,MDCK细胞培养物中病原体积累水平降低超过2.0对数,病毒特异性血凝素的形成受到超过90%的抑制。

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