Rezaizadeh Houman, Sanchez-Ross Monica, Kaluski Edo, Klapholz Marc, Haider Bunyad, Gerula Christine
New Jersey Medical School, Newark, NJ 07101, USA.
Acute Card Care. 2010 Mar;12(1):31-6. doi: 10.3109/17482940903578998.
Hypereosinophilic syndrome (HES) is a rare disorder of unregulated eosinophilia, which if untreated, may lead to systemic tissue infiltration and inflammation. Cardiac involvement is a common and serious associated complication. We describe a case of HES associated myocarditis mimicking a non-ST elevation MI (NSTEMI). Unlike myocarditis in general, our patient responded well to high dose methylprednisone, the standard of care in HES. We review the clinical presentation, pathophysiology, pathology and treatment of eosinophilic myocarditis related to HES.
高嗜酸性粒细胞综合征（HES）是一种罕见的、嗜酸性粒细胞不受控制的疾病，若不治疗，可能会导致全身组织浸润和炎症。心脏受累是一种常见且严重的相关并发症。我们描述了一例酷似非ST段抬高型心肌梗死（NSTEMI）的HES相关性心肌炎病例。与一般的心肌炎不同，我们的患者对高剂量甲基强的松龙（HES的标准治疗药物）反应良好。我们回顾了与HES相关的嗜酸性粒细胞性心肌炎的临床表现、病理生理学、病理学及治疗方法。
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