Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia.
Med J Aust. 2010 Mar 1;192(5):265-71. doi: 10.5694/j.1326-5377.2010.tb03504.x.
Cough is a common and distressing symptom that results in significant health care costs from medical consultations and medication use. Cough is a reflex activity with elements of voluntary control that forms part of the somatosensory system involving visceral sensation, a reflex motor response and associated behavioural responses. At the initial assessment for chronic cough, the clinician should elicit any alarm symptoms that might indicate a serious underlying disease and identify whether there is a specific disease present that is associated with chronic cough. If the examination, chest x-ray and spirometry are normal, the most common diagnoses in ADULTS are asthma, rhinitis or gastro-oesophageal reflux disease (GORD). The most common diagnoses in CHILDREN are asthma and protracted bronchitis. Management of chronic cough involves addressing the common issues of environmental exposures and patient or parental concerns, then instituting specific therapy. In ADULTS, conditions that are associated with removable causes or respond well to specific treatment include protracted bacterial bronchitis, angiotensin-converting enzyme inhibitor use, asthma, GORD, obstructive sleep apnoea and eosinophilic bronchitis. In CHILDREN, diagnoses that are associated with removable causes or respond well to treatment are exposure to environmental tobacco smoke, protracted bronchitis, asthma, motor tic, habit and psychogenic cough. In ADULTS, refractory cough that persists after therapy is managed by empirical inhaled corticosteroid therapy and speech pathology techniques.
咳嗽是一种常见且令人不适的症状,会导致医疗咨询和药物使用产生大量的医疗费用。咳嗽是一种反射活动,包含自愿控制的元素,是涉及内脏感觉的躯体感觉系统的一部分,包括反射运动反应和相关的行为反应。在慢性咳嗽的初始评估中,临床医生应引出任何可能表明潜在严重疾病的警示症状,并确定是否存在与慢性咳嗽相关的特定疾病。如果检查、胸部 X 光和肺功能检查正常,则成人最常见的诊断是哮喘、鼻炎或胃食管反流病(GORD)。儿童最常见的诊断是哮喘和迁延性支气管炎。慢性咳嗽的管理包括解决常见的环境暴露和患者或家长关注的问题,然后进行特定的治疗。在成人中,与可去除原因相关或对特定治疗反应良好的疾病包括迁延性细菌性支气管炎、血管紧张素转换酶抑制剂的使用、哮喘、GORD、阻塞性睡眠呼吸暂停和嗜酸性粒细胞性支气管炎。在儿童中,与可去除原因相关或对治疗反应良好的诊断包括接触环境烟草烟雾、迁延性支气管炎、哮喘、运动性抽搐、习惯和精神性咳嗽。在成人中,经过治疗后持续存在的难治性咳嗽通过经验性吸入皮质激素治疗和言语病理学技术来管理。