Department of Urology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Int J Urol. 2010 Apr;17(4):346-52. doi: 10.1111/j.1442-2042.2010.02467.x. Epub 2010 Mar 1.
To determine the prevalence of dysfunctional voiding (DV) in female stress urinary incontinence (SUI) and its modification after tension-free vaginal tape (TVT) procedure.
Three hundred and sixty women with SUI were enrolled and underwent urodynamics from 2002 to 2008. DV was determined when non-neurogenic detrusor-sphincter dyssynergia occurred during voluntary voiding. It was further quantitatively analyzed using the tense/loose value, a parameter derived from external anal sphincter electromyogram. The distribution of other urodynamic variables was also evaluated. One hundred and fifty patients underwent the TVT procedure and forty of them were studied with urodynamics after surgery during follow up.
Overall, DV was diagnosed in ninety-nine patients, with a prevalence of 27.5%. The functional profile length in SUI women with DV was significantly shorter than that in SUI women without DV (3.13 +/- 0.76 vs 3.32 +/- 0.65, P = 0.017). After the TVT procedure, the recovery of SUI between cases with and without DV showed no significant difference. The rate of DV state change after the surgery, namely from with to without DV or from without to with DV, significantly differed between the female patients with and without DV (66.7% vs 3.6%, P < 0.05) during follow up. The DV improved after the surgery in SUI women with DV.
DV might represent a coexistent finding in women with SUI. The main difference of women with SUI and DV, as compared with those without DV, is a shortened functional profile length. In such cases, TVT procedure can improve DV along with the treatment of SUI.
确定女性压力性尿失禁(SUI)中功能障碍性排尿(DV)的患病率及其在无张力阴道吊带(TVT)手术后的变化。
2002 年至 2008 年,我们共招募了 360 例 SUI 患者进行尿动力学检查。当在自愿排尿过程中出现非神经性逼尿肌-括约肌协同失调时,即诊断为 DV。采用外部肛门括约肌肌电图的紧张/松弛值对其进行进一步定量分析。还评估了其他尿动力学变量的分布。150 例患者接受了 TVT 手术,其中 40 例在随访期间接受了手术后的尿动力学检查。
总体而言,99 例患者诊断为 DV,患病率为 27.5%。DV 患者的功能性尿失禁形态长度明显短于无 DV 患者(3.13±0.76 对 3.32±0.65,P=0.017)。TVT 手术后,有和无 DV 的 SUI 患者的 SUI 恢复情况无显著差异。手术后 DV 状态变化(即从有到无或从无到有)的发生率在有和无 DV 的女性患者之间存在显著差异(66.7%对 3.6%,P<0.05)。SUI 伴 DV 的患者在手术后 DV 得到改善。
DV 可能是 SUI 女性的并存发现。与无 DV 的 SUI 女性相比,SUI 伴 DV 女性的主要区别是功能性尿失禁形态长度缩短。在这种情况下,TVT 手术可以改善 DV 以及 SUI 的治疗效果。