针对因神经肌肉功能缺陷导致逼尿肌活动低下的女性患者的低频电疗法。
Low-frequency electrotherapy for female patients with detrusor underactivity due to neuromuscular deficiency.
作者信息
Xu Dan-Feng, Zhang Shen, Wang Cun-Zhou, Li Jun, Qu Chuang-Yu, Cui Xin-Gang, Zhao Sheng-Jia
机构信息
Department of Urology, Changzheng Hospital, Second Military Medical University, No. 415, Fengyang Rd, Shanghai 200003, China.
出版信息
Int Urogynecol J. 2012 Aug;23(8):1007-15. doi: 10.1007/s00192-012-1714-2. Epub 2012 Mar 23.
INTRODUCTION AND HYPOTHESIS
The aim of the study was to assess the efficacy of low-frequency electrotherapy (LFE) for female patients with early-stage detrusor underactivity (DUA) due to neuromuscular deficiency.
METHODS
A total of 102 female patients were divided randomly into four groups: LFE-NC (normal compliance), LFE-LC (low compliance), CON (control)-NC and CON-LC. Patients in the LFE-NC and LFE-LC groups received LFE, and those in the CON-NC and CON-LC groups received conservative treatment. Urodynamic evaluation was performed before and after treatment.
RESULTS
After treatment, 82 % of the LFE-NC regained detrusor contractility, whereas only 2 (8 %) of the CON-NC had normal detrusor contraction. None of LFE-LC or CON-LC regained detrusor contractility (p < 0.01). The per cent of LFE-NC who relied on catheterization for bladder emptying decreased by 43 % (p < 0.01). Those in the LFE-LC, CON-NC and CON-LC groups decreased by only 4, 12 or 0 % (p > 0.05).
CONCLUSIONS
LFE was more effective for DUA patients with normal compliance; these patients benefited from LFE, but DUA patients with low compliance did not.
引言与假设
本研究旨在评估低频电疗法（LFE）对因神经肌肉功能缺陷导致的早期逼尿肌活动不足（DUA）女性患者的疗效。
方法
总共102名女性患者被随机分为四组：LFE-NC（正常顺应性）组、LFE-LC（低顺应性）组、CON（对照）-NC组和CON-LC组。LFE-NC组和LFE-LC组的患者接受LFE治疗，CON-NC组和CON-LC组的患者接受保守治疗。在治疗前后进行尿动力学评估。
结果结果
治疗后，82%的LFE-NC组患者恢复了逼尿肌收缩力，而CON-NC组只有2名（8%）患者的逼尿肌收缩正常。LFE-LC组和CON-LC组均无患者恢复逼尿肌收缩力（p<0.01）。LFE-NC组中依靠导尿排空膀胱的患者比例下降了43%（p<0.01）。LFE-LC组、CON-NC组和CON-LC组的这一比例仅分别下降了4%、12%或0%（p>0.05）。
结论
LFE对具有正常顺应性的DUA患者更有效；这些患者从LFE中受益，但顺应性低的DUA患者则不然。
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