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精索血管肌纤维母细胞瘤:一例报告

Angiomyofibroblastoma of the spermatic cord: a case report.

作者信息

Tzanakis Nikolaos E, Giannopoulos George A, Efstathiou Stamatis P, Rallis Georgios E, Nikiteas Nikolaos I

机构信息

4th Surgical Department, Attikon Hospital, University of Athens, (1 Rimini str), Athens, (124 62), Greece.

出版信息

J Med Case Rep. 2010 Mar 4;4:79. doi: 10.1186/1752-1947-4-79.

Abstract

INTRODUCTION

Angiomyofibroblastoma is a benign soft tissue tumor with tendency to arise in the vulva.

CASE PRESENTATION

We report a 36-year-old Greek Caucasian man presenting with a left inguinal painless mass. This is the second case of angiomyofibroblastoma of the spermatic cord. At operation, a 4.5 cm well-circumscribed solid tumor was found adherent to the spermatic cord. The tumor consisted of spindle-shaped cells proliferating in short fascicles between numerous medium-sized blood vessels with thin and hyalinized walls. Neoplastic cells had eosinophilic cytoplasm with neither mitotic figures nor nuclear atypia. The stroma included abundant mast cells and few mature lypocytes. Immunostaining showed positivity for vimentin, CD34, desmin and smooth muscle actin. Our patient was treated by simple excision and was followed up for five years with clinical examination and ultrasonography, revealing no evidence of local recurrence or metastasis.

CONCLUSION

This unusual neoplasm should be distinguished from aggressive angiomyxoma and other myxoid malignant tumors with widespread metastatic potential.

摘要

引言

血管肌成纤维细胞瘤是一种倾向于在外阴发生的良性软组织肿瘤。

病例报告

我们报告一名36岁的希腊白人男性,表现为左侧腹股沟无痛性肿块。这是精索血管肌成纤维细胞瘤的第二例病例。手术时,发现一个4.5厘米边界清晰的实性肿瘤附着于精索。肿瘤由短束状增生的梭形细胞组成,位于众多壁薄且玻璃样变的中等大小血管之间。肿瘤细胞有嗜酸性细胞质,无核分裂象及核异型性。间质中有丰富的肥大细胞和少量成熟淋巴细胞。免疫组化显示波形蛋白、CD34、结蛋白和平滑肌肌动蛋白呈阳性。我们的患者接受了单纯切除术,并通过临床检查和超声随访五年,未发现局部复发或转移的证据。

结论

这种不寻常的肿瘤应与侵袭性血管黏液瘤及其他具有广泛转移潜能的黏液样恶性肿瘤相鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/2838917/271d2e978db3/1752-1947-4-79-1.jpg

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