Tzanakis Nikolaos E, Giannopoulos George A, Efstathiou Stamatis P, Rallis Georgios E, Nikiteas Nikolaos I
4th Surgical Department, Attikon Hospital, University of Athens, (1 Rimini str), Athens, (124 62), Greece.
J Med Case Rep. 2010 Mar 4;4:79. doi: 10.1186/1752-1947-4-79.
Angiomyofibroblastoma is a benign soft tissue tumor with tendency to arise in the vulva.
We report a 36-year-old Greek Caucasian man presenting with a left inguinal painless mass. This is the second case of angiomyofibroblastoma of the spermatic cord. At operation, a 4.5 cm well-circumscribed solid tumor was found adherent to the spermatic cord. The tumor consisted of spindle-shaped cells proliferating in short fascicles between numerous medium-sized blood vessels with thin and hyalinized walls. Neoplastic cells had eosinophilic cytoplasm with neither mitotic figures nor nuclear atypia. The stroma included abundant mast cells and few mature lypocytes. Immunostaining showed positivity for vimentin, CD34, desmin and smooth muscle actin. Our patient was treated by simple excision and was followed up for five years with clinical examination and ultrasonography, revealing no evidence of local recurrence or metastasis.
This unusual neoplasm should be distinguished from aggressive angiomyxoma and other myxoid malignant tumors with widespread metastatic potential.
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