Department of Biology, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Epidemiol Infect. 2010 May;138(5):707-12. doi: 10.1017/S0950268810000440. Epub 2010 Mar 5.
Staphylococcus aureus is an important human pathogen and is a growing public health concern. In this study, 130 S. aureus, 93 methicillin-resistant S. aureus (MRSA) and 37 methicillin-sensitive S. aureus (MSSA), clinical isolates recovered from Lebanon were typed by protein A gene (spa) sequencing and multi-locus sequence typing (MLST). Forty-eight different spa types were identified and clustered into 30 different groups. MLST revealed 10 sequence types (STs) among the isolates. There were eight major MRSA clones defined as isolates with the same ST and the same SCCmec type. The majority of the PVL-positive isolates (53%) were ST80-MRSA-IVc. Systematic surveillance of both hospital and community isolates in Lebanon together with measures designed to limit the spread are required.
金黄色葡萄球菌是一种重要的人类病原体，也是日益受到关注的公共卫生问题。本研究对从黎巴嫩分离的 130 株金黄色葡萄球菌、93 株耐甲氧西林金黄色葡萄球菌（MRSA）和 37 株甲氧西林敏感金黄色葡萄球菌（MSSA）进行了蛋白 A 基因（spa）测序和多位点序列分型（MLST）。共鉴定出 48 种不同的 spa 型，分为 30 个不同的组。MLST 显示，这些分离株中有 10 种序列型（ST）。8 种主要的 MRSA 克隆被定义为具有相同 ST 和相同 SCCmec 型的分离株。大多数 PVL 阳性分离株（53%）为 ST80-MRSA-IVc。需要对黎巴嫩的医院和社区分离株进行系统监测，并采取措施限制其传播。
