MGH Weight Center and Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, 50 Staniford Street, Boston, MA 02114, USA.
Gastroenterol Clin North Am. 2010 Mar;39(1):69-79. doi: 10.1016/j.gtc.2010.01.001.
This article examines the transitions in pharmacological therapy for obesity. It reviews the current options approved by the Food and Drug Administration and several drugs approved for other indications that can be used to treat obesity as well. Because weight regulation is complex and redundant systems protect against perceived starvation, optimal treatment of obesity in individual patients will likely require different combinations of behavioral, nutritional, pharmacologic, endoscopic, and surgical therapies.
本文探讨了肥胖症药物治疗的转变。它回顾了美国食品和药物管理局批准的当前选择，以及几种批准用于其他适应症的药物，这些药物也可用于治疗肥胖症。由于体重调节复杂，冗余系统可以防止感知到的饥饿，因此，个体患者的肥胖症的最佳治疗可能需要行为、营养、药理、内镜和手术治疗的不同组合。
