Faculté de Médecine et des Sciences de la Santé, Université de Brest, EA 3882, 29200 Brest, France.
Laboratoire de Microbiologie, Centre Hospitalier Universitaire La Cavale Blanche, Boulevard Tanguy Prigent, 29609 Brest cedex, France.
J Med Microbiol. 2010 Jun;59(Pt 6):733-735. doi: 10.1099/jmm.0.016881-0. Epub 2010 Mar 4.
Congenital tuberculosis (TB) remains a rare disease but is fatal if untreated. Early detection is difficult because of the non-specific nature of the symptoms in TB during pregnancy and infancy. This report summarizes a case of congenital TB in a very premature infant, born at 25 weeks gestation. Miliary TB was diagnosed in the mother when the neonate was 20 days old. Antituberculous therapy allowed a rapid improvement in the mother. The infant died at 27 days old. A Beijing genotype strain of Mycobacterium tuberculosis was isolated both in the mother, from pulmonary and urine specimens, and in the infant, from peritoneal fluid.
先天性结核病（TB）仍然是一种罕见的疾病，但如果不治疗则致命。由于妊娠和婴儿期结核病症状的非特异性，早期发现很困难。本报告总结了一例非常早产婴儿的先天性结核病病例，该婴儿于 25 周时出生。当新生儿 20 天时，母亲被诊断为粟粒性结核病。抗结核治疗使母亲迅速好转。婴儿在 27 天时死亡。从母亲的肺部和尿液标本以及婴儿的腹腔液中均分离出了北京基因型结核分枝杆菌。
