DiGeorge syndrome, Tbx1, and retinoic acid signaling come full circle.
作者信息
Yutzey Katherine E
出版信息
Circ Res. 2010 Mar 5;106(4):630-2. doi: 10.1161/CIRCRESAHA.109.215319.
Abstract
摘要
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DiGeorge syndrome, Tbx1, and retinoic acid signaling come full circle.迪格奥尔格综合征、Tbx1与视黄酸信号转导形成了一个完整的循环。
Circ Res. 2010 Mar 5;106(4):630-2. doi: 10.1161/CIRCRESAHA.109.215319.
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本文引用的文献
1
Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome.胚胎视黄酸合成水平降低可加速 DiGeorge 综合征小鼠模型中动脉生长延迟的恢复。
Circ Res. 2010 Mar 5;106(4):686-94. doi: 10.1161/CIRCRESAHA.109.205732. Epub 2010 Jan 28.
2
Retinoic acid in development: towards an integrated view.发育过程中的视黄酸：迈向综合视角。
Nat Rev Genet. 2008 Jul;9(7):541-53. doi: 10.1038/nrg2340. Epub 2008 Jun 10.
3
Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick.Cyp26基因a1、b1和c1在Tbx1基因敲除小鼠中表达下调，抑制Cyp26酶功能会在鸡中产生与DiGeorge综合征相似的表型。
Hum Mol Genet. 2006 Dec 1;15(23):3394-410. doi: 10.1093/hmg/ddl416. Epub 2006 Oct 17.
4
Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome.22q11缺失综合征模型中Tbx1与Crkl的剂量依赖性相互作用及局部异常视黄酸信号传导
Dev Cell. 2006 Jan;10(1):81-92. doi: 10.1016/j.devcel.2005.12.002.
5
Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes.Crkl基因缺陷在22q11缺失综合征小鼠模型中破坏Fgf8信号通路。
Dev Cell. 2006 Jan;10(1):71-80. doi: 10.1016/j.devcel.2005.12.003.
6
Dissecting contiguous gene defects: TBX1.剖析相邻基因缺陷：TBX1
Curr Opin Genet Dev. 2005 Jun;15(3):279-84. doi: 10.1016/j.gde.2005.03.001.
7
Retinoic acid down-regulates Tbx1 expression in vivo and in vitro.维甲酸在体内和体外均下调Tbx1的表达。
Dev Dyn. 2005 Apr;232(4):928-38. doi: 10.1002/dvdy.20268.
8
An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation.母体维生素A缺乏所致畸形综合征的分析。孕期不同时间补充维生素A的效果。
Am J Anat. 1953 Mar;92(2):189-217. doi: 10.1002/aja.1000920202.
9
Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice.胚胎视黄酸合成减少导致新生小鼠出现迪格奥尔格综合征表型。
Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1763-8. doi: 10.1073/pnas.0437920100. Epub 2003 Jan 31.
10
A genetic link between Tbx1 and fibroblast growth factor signaling.Tbx1与成纤维细胞生长因子信号传导之间的遗传联系。
Development. 2002 Oct;129(19):4605-11. doi: 10.1242/dev.129.19.4605.
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