Fernández María F, Samela Patricia C, Buján María M, Merediz Javier, Pierini Adrián M
Servicio de Dermatología, Hospital Nacional de Pediatría Prof. Dr. Juan P. Garrahan.
Arch Argent Pediatr. 2010 Feb;108(1):e5-8. doi: 10.1590/S0325-00752010000100015.
We report the case of an 8-days-old patient with linear rows of vesiculobullous lesions from birth. Along with these lesions, the neonate had eosinophilia, which made us arrive to the clinical diagnosis of Incontinentia Pigmenti. Incontinentia Pigmenti or Bloch Sulzberger disease is a multisystemic neuroectodermal disorder that affects mostly women, which includes as initial manifestation cutaneous lesions that evolve by outbreaks. Occasionally, it is associated with neurologic, ophthalmologic, and dental compromise. This must be considered as a differential diagnosis when a neonate presents vesiculobullous lesions.
我们报告了一例8日龄自出生起即有呈线性排列的水疱大疱性皮损的患者。除了这些皮损外,该新生儿还有嗜酸性粒细胞增多症,这使我们得出色素失禁症的临床诊断。色素失禁症或布洛赫-苏尔茨贝格病是一种多系统神经外胚层疾病,主要影响女性,其初始表现包括皮肤损害,这些损害会成批出现并演变。偶尔,它还与神经、眼科和牙科损害相关。当新生儿出现水疱大疱性皮损时,必须将其视为鉴别诊断之一。