Leeds Institute of Health Sciences, University of Leeds, UK.
Psychol Health. 2010 Dec;25(10):1175-94. doi: 10.1080/08870440903055893.
Research considering the role of attitudes in prenatal testing choices has commonly focused on the relationship between the attitude towards undergoing testing and actual testing behaviour. In contrast, this study focused on the relationship between testing behaviour and attitudes towards the targets of the behaviour (in this case people with Down syndrome (DS) and having a baby with DS). A cross-sectional, prospective survey of 197 pregnant women measured attitudes towards the targets of prenatal testing along with intentions to use screening and diagnostic testing, and the termination of an affected pregnancy. Screening uptake was established via patient records. Although attitudes towards DS and having a baby with DS were significantly associated with screening uptake and testing and termination intentions, unfavourable attitudes were better than favourable ones at predicting these outcomes. For example, in the quartile of women with the 'most favourable' attitude towards people with DS 67% used screening although only 8% said they would terminate an affected pregnancy. Qualitative data suggested that not all women considered personal attitudes towards DS to be relevant to their screening decisions. This finding has implications for the way in which informed choice is currently understood and measured in the prenatal testing context.
研究考虑了态度在产前检测选择中的作用，通常侧重于检测态度与实际检测行为之间的关系。相比之下，本研究侧重于检测行为与行为目标（在这种情况下是唐氏综合征患者和唐氏综合征婴儿）的态度之间的关系。对 197 名孕妇进行的横断面前瞻性调查测量了对产前检测目标的态度，以及对筛查和诊断检测的使用意愿，以及终止受影响妊娠的意愿。通过患者记录确定了筛查的采用情况。尽管对唐氏综合征和唐氏综合征婴儿的态度与筛查的采用以及检测和终止的意愿显著相关，但不利的态度比有利的态度更能预测这些结果。例如，在对唐氏综合征患者“最有利”的态度四分位数中，有 67%的女性使用了筛查，尽管只有 8%的女性表示她们会终止受影响的妊娠。定性数据表明，并非所有女性都认为个人对唐氏综合征的态度与她们的筛查决策相关。这一发现对目前在产前检测背景下理解和衡量知情选择的方式具有影响。
