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帕金森病中的消化系统疾病:胃动力不足、吸收不良与便秘

[Digestive disorders in Parkinson's disease: gastric atony, malabsorption and constipation].

作者信息

Pérez-Macho L, Borja-Andrés S

机构信息

Hospital Virgen de la Concha, Zamora, España.

出版信息

Rev Neurol. 2010 Feb 8;50 Suppl 2:S55-8.

Abstract

INTRODUCTION

Constipation and gastric atony are two of the most important non-motor symptoms of the disease. The first is made significant by its high prevalence and precocity, since it may appear several years before the motor symptoms, and the second because of the repercussions it has on the absorption of oral medication used in this disease.

DEVELOPMENT

Both the symptoms and their possible treatment are reviewed.

CONCLUSIONS

In both cases treatment is based on hygienic-dietary measures that avoid substances that reduce peristalsis, prokinetic drugs like domperidone and, sometimes, infiltration of botulinum toxin, electrical stimulation or even surgical treatment.

摘要

引言

便秘和胃无力是该疾病最重要的两种非运动症状。前者因其高发病率和早熟而显著,因为它可能在运动症状出现前数年就出现,而后者则因其对该疾病口服药物吸收的影响。

发展

对症状及其可能的治疗方法进行了综述。

结论

在这两种情况下,治疗都基于卫生饮食措施,即避免使用减少蠕动的物质、使用多潘立酮等促动力药物,有时还包括肉毒杆菌毒素注射、电刺激甚至手术治疗。

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