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对 37 名偏头痛患者进行神经反馈和生物反馈:一项临床结果研究。

Neurofeedback and biofeedback with 37 migraineurs: a clinical outcome study.

机构信息

The Better Brain Center, Inc, 2121 Eisenhower Ave Suite 604 Alexandria, VA 22314, USA.

出版信息

Behav Brain Funct. 2010 Feb 2;6:9. doi: 10.1186/1744-9081-6-9.

Abstract

BACKGROUND

Traditional peripheral biofeedback has grade A evidence for effectively treating migraines. Two newer forms of neurobiofeedback, EEG biofeedback and hemoencephalography biofeedback were combined with thermal handwarming biofeedback to treat 37 migraineurs in a clinical outpatient setting.

METHODS

37 migraine patients underwent an average of 40 neurofeedback sessions combined with thermal biofeedback in an outpatient biofeedback clinic. All patients were on at least one type of medication for migraine; preventive, abortive or rescue. Patients kept daily headache diaries a minimum of two weeks prior to treatment and throughout treatment showing symptom frequency, severity, duration and medications used. Treatments were conducted an average of three times weekly over an average span of 6 months. Headache diaries were examined after treatment and a formal interview was conducted. After an average of 14.5 months following treatment, a formal interview was conducted in order to ascertain duration of treatment effects.

RESULTS

Of the 37 migraine patients treated, 26 patients or 70% experienced at least a 50% reduction in the frequency of their headaches which was sustained on average 14.5 months after treatments were discontinued.

CONCLUSIONS

All combined neuro and biofeedback interventions were effective in reducing the frequency of migraines with clients using medication resulting in a more favorable outcome (70% experiencing at least a 50% reduction in headaches) than just medications alone (50% experience a 50% reduction) and that the effect size of our study involving three different types of biofeedback for migraine (1.09) was more robust than effect size of combined studies on thermal biofeedback alone for migraine (.5). These non-invasive interventions may show promise for treating treatment-refractory migraine and for preventing the progression from episodic to chronic migraine.

摘要

背景

传统的外周生物反馈疗法在治疗偏头痛方面具有 A 级证据。两种较新的神经生物反馈形式,即脑电图生物反馈和脑血流图生物反馈,与手部热反馈生物反馈相结合,用于治疗 37 名偏头痛患者的临床门诊。

方法

37 名偏头痛患者在一家门诊生物反馈诊所接受了平均 40 次神经反馈治疗,同时结合热生物反馈治疗。所有患者均至少服用过一种偏头痛药物,包括预防、止痛或急救药物。患者在治疗前至少两周和治疗期间每天记录头痛日记,记录症状频率、严重程度、持续时间和使用的药物。治疗平均每周进行三次,持续 6 个月。治疗后检查头痛日记,并进行正式访谈。治疗后平均 14.5 个月进行正式访谈,以确定治疗效果的持续时间。

结果

在接受治疗的 37 名偏头痛患者中,26 名患者(70%)头痛发作频率至少降低了 50%,且这种效果平均持续 14.5 个月,之后停止了治疗。

结论

所有联合神经和生物反馈干预措施都有效减少了偏头痛的发作频率,与单独使用药物相比(50%的患者头痛频率降低 50%),使用药物的患者结果更好(70%的患者头痛频率降低 50%),而且我们的研究涉及三种不同类型的偏头痛生物反馈(1.09)的效果大小比单纯热生物反馈治疗偏头痛的联合研究的效果大小(0.5)更稳健。这些非侵入性干预措施可能对治疗难治性偏头痛和预防从偶发性偏头痛向慢性偏头痛的进展具有一定的应用前景。

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