Akbulut Sami, Senol Ayhan, Cakabay Bahri, Sezgin Arsenal
Department of Surgery, Diyarbakir Education and Research Hospital, Op Dr Seref Inaloz Caddesi, 21400, Diyarbakir, Turkey.
J Med Case Rep. 2010 Feb 17;4:52. doi: 10.1186/1752-1947-4-52.
Renal oncocytomas are benign neoplasms derived from cells of the distal renal tubule, and comprise 5% to 7% of primary renal neoplasms. Oncocytomas are mostly asymptomatic, and the majority of tumors are discovered incidentally. In this case report, we present a case of a patient with a giant oncocytoma arising from her left kidney.
We describe a 25-year-old Turkish woman who was admitted to our hospital with abdominal pain and a 3-year palpable abdominal mass, which was found present since her second pregnancy. Examination revealed a 15 x 20-cm mass in her abdominal cavity. Computed tomography revealed a mass with regular outlines, measuring 18 x 11 x 12 cm, associated with the left kidney, and causing marked hydroureteronephrosis. We excised the mass and performed a left nephrectomy on our patient. The immunohistopathology of the mass was consistent with renal oncocytoma. No local or distant metastasis was seen at 6 months postoperatively.
To the best of our knowledge, this is the second largest renal oncocytoma described in the English language literature. This is also the first reported giant oncocytoma that presented during pregnancy.
肾嗜酸细胞瘤是源自远端肾小管细胞的良性肿瘤，占原发性肾肿瘤的5%至7%。嗜酸细胞瘤大多无症状，大多数肿瘤是偶然发现的。在本病例报告中，我们介绍了一名左肾出现巨大嗜酸细胞瘤的患者。
我们描述了一名25岁的土耳其女性，她因腹痛和一个可触及的腹部肿块入院，该肿块自她第二次怀孕以来就已存在。检查发现她腹腔内有一个15×20厘米的肿块。计算机断层扫描显示一个轮廓规则的肿块，大小为18×11×12厘米，与左肾相关，并导致明显的肾盂输尿管积水。我们切除了肿块并对患者进行了左肾切除术。肿块的免疫组织病理学与肾嗜酸细胞瘤一致。术后6个月未见局部或远处转移。
据我们所知，这是英文文献中描述的第二大肾嗜酸细胞瘤。这也是首次报道的在怀孕期间出现的巨大嗜酸细胞瘤。
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