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[肾嗜酸细胞瘤:14例报告及文献复习]

[Renal oncocytoma: report of 14 cases and review of the literature].

作者信息

Monge Mirallas J M, Gutiérrez Baños J L, Martín Garcia B, Hernandez Rodríguez R, Portillo Martín J A, Correas Gómez M A, Roca Edreira A

机构信息

Servicio de Urología, Hospital Universitario Marqués de Valdecilla, Santander, España.

出版信息

Arch Esp Urol. 1994 Jul-Aug;47(6):564-70.

PMID:7944597
Abstract

Renal oncocytoma is an uncommon tumor. Of 223 renal tumors that were treated at our institution from 1970-1991, 14 (6.2%) were oncocytomas [9 females (65%) and 5 males (35%)]. The highest incidence was observed in the sixth decade (60.7 yrs). Tumor size range from 2 to 19 cm in diameter (mean = 8.07 cm); 11 (78.5%) were localized in the right kidney, principally in the superior pole. The tumor was incidentally discovered in 8 cases (57%); 1 case presented Wunderlich's syndrome; 1 had a palpable renal mass; 6 had abdominal pain. All the tumors were confined to the kidney. Thirteen were Robson stage I and 1 stage II. According to the UICC classification, 12 were T1, 1 T2 and 1 T3. All tumors were N0 M0. Patient evaluation included IVP (6), US (12), CT (14) and selective renal arteriography (2). The typical angiographic patterns were not observed in these 2 cases. Concerning the CT findings, in 8 cases (57%) the first diagnosis discarded was that of hypernephroma, although there were also signs suggestive of oncocytoma. Six cases (43%) showed signs indicating oncocytoma as first diagnosis. All patients were submitted to radical nephrectomy, which achieved good results in all cases at 7 months' to 5 years' follow up.

摘要

肾嗜酸细胞瘤是一种罕见的肿瘤。1970年至1991年在我们机构接受治疗的223例肾肿瘤中,14例(6.2%)为嗜酸细胞瘤[9例女性(65%)和5例男性(35%)]。最高发病率出现在第六个十年(60.7岁)。肿瘤直径范围为2至19厘米(平均=8.07厘米);11例(78.5%)位于右肾,主要在上极。8例(57%)肿瘤为偶然发现;1例出现肾出血性梗死综合征;1例可触及肾脏肿块;6例有腹痛。所有肿瘤均局限于肾脏。13例为罗布森I期,1例为II期。根据国际抗癌联盟(UICC)分类,12例为T1,1例为T2,1例为T3。所有肿瘤均为N0 M0。患者评估包括静脉肾盂造影(IVP,6例)、超声(US,12例)、CT(14例)和选择性肾动脉造影(2例)。这2例未观察到典型的血管造影模式。关于CT表现,8例(57%)最初排除的诊断为肾细胞癌,尽管也有提示嗜酸细胞瘤的征象。6例(43%)表现出提示嗜酸细胞瘤为最初诊断的征象。所有患者均接受了根治性肾切除术,在7个月至5年的随访中,所有病例均取得了良好效果。

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