Takashi M, Murase T, Goto M, Mitsuya H, Koshikawa T
Hinyokika Kiyo. 1985 Aug;31(8):1445-51.
A case of renal oncocytoma is reported. A 56-year-old woman was admitted with the complaint of an abdominal mass. Right transabdominal nephrectomy was performed on January 23, 1984. The resected kidney weighed 262 g and contained a well-demarcated 5 X 5 X 4 cm tumor in the middle portion. The cross section of the tumor was tan-brown. Light microscopic examination disclosed that the greater part of the tumor was composed of cells with abundant, and finely granular eosinophilic cytoplasm and with moderate nuclear pleomorphism. Electron microscopic examination confirmed that the cytoplasm had numerous mitochondria and few other organelles. According to these findings, the tumor was diagnosed as renal oncocytoma. Furthermore, it is noteworthy that in this case there were tubular arrangement of the cells resembling proximal renal tubules in a focal area and a group of cells with considerable nuclear atypia and hyperchromatism in another area. The patient has been well without any local recurrence or distant metastasis ten months after the operation. In addition, fourteen cases of renal oncocytoma in Japan, including the present case, are reviewed.
报告一例肾嗜酸细胞瘤。一名56岁女性因腹部肿块主诉入院。1984年1月23日行右经腹肾切除术。切除的肾脏重262g，中部有一个边界清晰的5×5×4cm肿瘤。肿瘤切面呈棕褐色。光镜检查显示，肿瘤大部分由细胞组成，这些细胞具有丰富的、细颗粒状嗜酸性细胞质，核中度异形。电镜检查证实细胞质中有大量线粒体，其他细胞器很少。根据这些发现，肿瘤被诊断为肾嗜酸细胞瘤。此外，值得注意的是，在该病例中，在一个局灶区域有类似近端肾小管的细胞呈管状排列，在另一个区域有一组具有相当核异型性和核深染的细胞。患者术后十个月情况良好，无任何局部复发或远处转移。此外，对包括本病例在内的日本14例肾嗜酸细胞瘤病例进行了回顾。
