Medizinische Klinik II und Klinik für Palliativmedizin, Klinikum Aschaffenburg, Akademisches Lehrkrankenhaus der Universität Würzburg, Germany.
Best Pract Res Clin Gastroenterol. 2010 Feb;24(1):13-7. doi: 10.1016/j.bpg.2009.11.003.
Type of lymphoma and stage of disease are the two decisive prognostic factors and therapeutic determinants. For the locoregional staging, i.e. assessment of the gastric wall infiltration and perigastric lymphonodular involvement, endoscopic ultrasound (EUS) is highly useful. EUS has, therefore, to be integrated into the standard staging procedure of gastric lymphoma, although its impact on initial treatment decisions might be limited in the individual case. A benefit from the use of miniechoendoscopes, EUS elastography and EUS-guided biopsies has not yet been proven in gastric lymphoma. EUS also confers an important prognostic value regarding treatment responses to Helicobacter pylori eradication. On the contrary, EUS cannot be recommended as a regular part of follow-up investigations considering its limited value in predicting the response of the lymphoma to radiation or chemotherapy.
淋巴瘤类型和疾病分期是两个决定性的预后因素和治疗决定因素。对于局部区域分期,即评估胃壁浸润和胃周淋巴结受累情况,内镜超声(EUS)非常有用。因此,EUS 必须纳入胃淋巴瘤的标准分期程序,尽管其对初始治疗决策的影响在个别情况下可能有限。在胃淋巴瘤中,使用微型回声内镜、EUS 弹性成像和 EUS 引导下活检尚未证明有益。EUS 还对治疗幽门螺杆菌根除的反应具有重要的预后价值。相反,EUS 不能作为常规随访检查的一部分,因为它在预测淋巴瘤对放疗或化疗的反应方面价值有限。