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[兔经副流感嗜血杆菌 3 型、腺病毒 I 型和牛传染性鼻气管炎病毒联合抗原免疫后的血清学反应]

[Serological response of rabbits following immunization with M. parainfluenzae-3, adenovirus I and infectious bovine rhinotracheitis virus associated antigens].

作者信息

Tsvetkov P

出版信息

Vet Med Nauki. 1977;14(6):33-6.

PMID:202065
Abstract

The immunization of rabbits separately with virus suspensions of Myxovirus parainfluenzae-3, adenovirus serotype I, and bovine rhinotracheitis virus or with combinations of each two of them and with a combination of all three viruses led to the production of sera having titers of virus-neutralizing antibodies acting against each of the antigens that participated in the combination. Results showed that no inhibition existed of the antigens during immunization as established by the serologic response of the rabbits. The demonstrated specificity of the monovalent sera points to the fact that the latter could be used for the diagnostic purposes.

摘要

分别用副流感病毒3型、腺病毒1型和牛鼻气管炎病毒的病毒悬液,或用其中每两种病毒的组合以及三种病毒的组合对家兔进行免疫,结果产生了具有针对参与组合的每种抗原的病毒中和抗体效价的血清。结果表明,根据家兔的血清学反应确定,免疫过程中不存在抗原抑制现象。单价血清所显示的特异性表明,单价血清可用于诊断目的。

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