Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
J Clin Anesth. 2010 Feb;22(1):64-70. doi: 10.1016/j.jclinane.2009.03.010.
Transient left ventricular apical ballooning syndrome (TLVAB), also known as Takotsubo cardiomyopathy, is a cardiac syndrome characterized by transient left ventricular dysfunction in the absence of obstructive atherosclerotic coronary artery disease. An episode of emotional and/or physiologic stress frequently precedes presentation of this syndrome. TLVAB may initially present as an acute coronary syndrome characterized by chest pain, pulmonary edema, electrocardiographic changes, elevated cardiac enzymes, and cardiogenic shock. This syndrome is still underestimated today and the potential appearance of TLVAB during the perioperative period can be a great challenge. Adequate beta-blockade is the mainstay in the treatment of patients with TLVAB during the acute phase and also for long-term management.
一过性左心室心尖球囊样综合征（TLVAB），也称心尖球形综合征，是一种以左心室短暂性功能障碍为特征的心脏综合征，不存在阻塞性动脉粥样硬化性冠状动脉疾病。该综合征通常在情绪和/或生理应激后发作。TLVAB 最初表现为急性冠状动脉综合征，特征为胸痛、肺水肿、心电图改变、心肌酶升高和心源性休克。目前，该综合征仍被低估，围手术期 TLVAB 的潜在表现可能是一个巨大的挑战。在急性发作期和长期管理中，充分的β受体阻滞剂是 TLVAB 患者的主要治疗方法。
