Department of Neurology, Far Eastern Memorial Hospital, Nan-Ya S. Rd., Sec.2 Pan-Chiao, Taipei, Taiwan, ROC.
Arch Gerontol Geriatr. 2011 Jan-Feb;52(1):60-5. doi: 10.1016/j.archger.2010.01.021. Epub 2010 Mar 5.
This study was designed to test the performance and related factors of a self-administered instrument in assessing behavioral and psychological symptoms of dementia (BPSD) by family caregivers. We recruited 173 patients with dementia and major caregivers from two neurological clinics. Information about clinical diagnosis, the Mini Mental State Examination (MMSE), the Clinical Dementia Rating (CDR), the Dementia Behavior Disturbance Inventory (DBDI), and global caregivers' strain were collected from interview and chart review. We found that DBDI has acceptable construct validity and good internal consistency reliability. BPSD was more frequently found in patients with advanced dementia, poor cognitive function and highly correlated to caregivers' strain. Multivariate analysis revealed that female patients and caregivers, advanced CDR stages, patient-caregiver relationship, types of dementia and MMSE score were related to the increase of frequency and disturbance index of DBDI. We concluded that BPSD could be evaluated by family caregivers using a self-administered instrument. Further study is indicated to clarify how caregiver characteristics affect the report of behavioral symptoms, and its clinical importance.
本研究旨在测试一种由家庭照顾者自行评估痴呆患者行为和心理症状（BPSD）的工具的性能及其相关因素。我们招募了来自两个神经科诊所的 173 名痴呆症患者和主要照顾者。通过访谈和病历回顾收集了关于临床诊断、简易精神状态检查（MMSE）、临床痴呆评定量表（CDR）、痴呆行为障碍量表（DBDI）和全球照顾者负担的信息。我们发现 DBDI 具有可接受的结构效度和良好的内部一致性信度。BPSD 在痴呆程度较重、认知功能较差的患者中更为常见，且与照顾者的负担高度相关。多变量分析显示，女性患者和照顾者、较高的 CDR 分期、患者-照顾者关系、痴呆类型和 MMSE 评分与 DBDI 的频率和干扰指数增加有关。我们得出结论，家庭照顾者可以使用自我管理工具评估 BPSD。进一步的研究需要阐明照顾者特征如何影响行为症状的报告，以及其临床重要性。
