Institute of Cell Biology, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Schafmattstrasse 18, 8093 Zurich, Switzerland.
Cell Stem Cell. 2010 Mar 5;6(3):189-91. doi: 10.1016/j.stem.2010.02.004.
In a recent paper in Nature, Vierbuchen et al. (2010) show that fibroblasts can be directly converted into functional neurons by defined factors. This finding sheds new light on the biology underlying cell-fate restrictions and might offer a new avenue for studying neurological diseases.
在最近发表在《自然》杂志上的一篇论文中，Vierbuchen 等人（2010 年）表明，成纤维细胞可以通过特定的因子直接转化为功能性神经元。这一发现为细胞命运限制的生物学基础提供了新的线索，并可能为研究神经疾病提供新的途径。
