Doddoli C, Trousse D, Avaro J-P, Djourno X-B, Giudicelli R, Fuentes P, Thomas P
Service de Chirurgie Thoracique et des Maladies de l'Oesophage, Hôpital Sainte-Marguerite, 270 boulevard de Sainte-Marguerite, 13274 Marseille cedex 9, France.
Rev Pneumol Clin. 2010 Feb;66(1):71-80. doi: 10.1016/j.pneumo.2009.12.013. Epub 2010 Feb 24.
Acute mediastinitis is a life-threatening complication (20 to 40 % of mortality) secondary to oropharyngeal abscesses, neck infections or oesophageal leak spreading into the mediastium. Early diagnosis and optimal therapeutic approach are crucial for patient survival. CT scanning of the cervical and thoracic area is a useful tool for diagnosis and follow-up. Treatment is based on broad-spectrum antibiotherapy, adequate surgery, mediastinal drainage, and treatment of possible organ failure. There is no surgical standardized attitude. Mini-invasive approach could be satisfactory when prompt diagnosis is established and the thoracic drainage is effective. Repeated postoperative CT scanning and close clinical and laboratory monitoring could make an additional thoracotomy a second-line procedure.
急性纵隔炎是一种危及生命的并发症(死亡率为20%至40%),继发于口咽脓肿、颈部感染或食管漏蔓延至纵隔。早期诊断和最佳治疗方法对患者生存至关重要。颈部和胸部的CT扫描是诊断和随访的有用工具。治疗基于广谱抗生素治疗、适当的手术、纵隔引流以及对可能出现的器官衰竭的治疗。目前尚无标准化的手术方式。当能迅速确诊且胸腔引流有效时,微创方法可能令人满意。术后重复进行CT扫描以及密切的临床和实验室监测可使再次开胸成为二线治疗手段。