Ney Douglas E, Huse Jason T, Dunkel Ira J, Steinherz Peter G, Haque Sofia, Khakoo Yasmin
Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
J Child Neurol. 2010 Oct;25(10):1292-5. doi: 10.1177/0883073810362267. Epub 2010 Mar 5.
Meningiomas are among the most common brain tumors in adults. They are most commonly located over the cerebral convexities and are infrequently found in an intraventricular location. Ionizing cranial radiation is a risk factor for late occurrence of meningiomas within the radiation field. While pathologic grading of meningiomas is straightforward, significant variability often exists between pathologists in applying standard grading criteria. This has implications for prognosis. Radiation-induced meningiomas may also have predilection to recur. The authors describe a case of an intraventricular meningioma occurring 23 years after cranial irradiation for childhood acute lymphoblastic leukemia.
脑膜瘤是成人中最常见的脑肿瘤之一。它们最常位于大脑凸面，很少见于脑室内。电离性颅脑辐射是辐射野内脑膜瘤晚期发生的危险因素。虽然脑膜瘤的病理分级很简单，但在应用标准分级标准时，病理学家之间往往存在很大差异。这对预后有影响。辐射诱发的脑膜瘤也可能易于复发。作者描述了一例儿童急性淋巴细胞白血病接受颅脑照射23年后发生的脑室内脑膜瘤病例。
