Widness John A
Department of Pediatrics, Carver College of Medicine, The University of Iowa, Iowa City, Ia.
Neoreviews. 2008 Nov 1;9(11):526-533. doi: 10.1542/neo.9-11-e526.
Because red blood cell (RBC) transfusion therapy remains the primary treatment of anemia encountered in early life, the basis for RBC transfusion in the treatment of symptomatic anemia is discussed in this review along with several important aspects of neonatal blood banking practices. Nontransfusion approaches to the prevention and treatment of neonatal anemia also are described. Finally, this review covers the controversy surrounding whether neonatal RBC transfusion therapy should be restrictive or liberal. The evaluation and treatment of uncommon and rare acquired and genetic causes of anemia in newborn infants are beyond the scope of this review.
由于红细胞(RBC)输血疗法仍然是早期生命中所遇到贫血的主要治疗方法,本综述讨论了有症状性贫血治疗中RBC输血的依据以及新生儿血库操作的几个重要方面。还描述了预防和治疗新生儿贫血的非输血方法。最后,本综述涵盖了围绕新生儿RBC输血疗法应严格还是宽松的争议。新生儿罕见和稀有获得性及遗传性贫血原因的评估和治疗不在本综述范围内。