van Asten W N, Beijneveld W J, Pieters B R, van Lier H J, Wijn P F, Skotnicki S H
Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands.
Surgery. 1991 May;109(5):633-9.
Aortoiliac obstructive disease was assessed by Doppler spectrum analysis of blood flow velocities in the common femoral artery measured both at rest and during reactive hyperemia. The intraarterial femoral artery pressure measured at rest and during reactive hyperemia served as the "gold standard" for the definition of a hemodynamically significant aortoiliac stenosis. Our results, obtained from 93 patients (136 limbs), showed that differences between Doppler spectra obtained from limbs with a hemodynamically significant aortoiliac stenosis and those from limbs without were more pronounced during reactive hyperemia than at rest. The best assessment of aortoiliac obstructive disease could be obtained with a combination of parameters derived from Doppler spectra measured at rest and during reactive hyperemia. With these parameters, obtained by multivariate analysis, 85% of the limbs were diagnosed correctly compared with the gold standard. If angiographic data were added to the gold standard, even 91% of the limbs were diagnosed correctly. We conclude that analysis of Doppler spectra-obtained noninvasively from the common femoral artery at rest and during reactive hyperemia provides an accurate hemodynamic assessment of the aortoiliac segment.
通过对静息状态和反应性充血期间股总动脉血流速度进行多普勒频谱分析来评估主髂动脉阻塞性疾病。静息状态和反应性充血期间测量的股动脉内压力作为血流动力学上显著的主髂动脉狭窄定义的“金标准”。我们对93例患者（136条肢体）的研究结果表明，在反应性充血期间，血流动力学上显著的主髂动脉狭窄肢体与无狭窄肢体的多普勒频谱差异比静息时更明显。结合静息状态和反应性充血期间测量的多普勒频谱得出的参数，可对主髂动脉阻塞性疾病进行最佳评估。通过多变量分析获得的这些参数，与金标准相比，85%的肢体诊断正确。如果将血管造影数据添加到金标准中，甚至91%的肢体诊断正确。我们得出结论，对静息状态和反应性充血期间股总动脉进行无创性多普勒频谱分析，可为主髂动脉段提供准确的血流动力学评估。
