Allergy, Clinical Immunology and Rheumatology Section of Department of Pediatrics at Federal University of São Paulo/ Paulista School of Medicine - São Paulo, Brazil.
J Bras Pneumol. 2010 Jan-Feb;36(1):124-33. doi: 10.1590/s1806-37132010000100017.
The objective of this review was to present evidence of the relationship between allergic rhinitis and impairment of quality of life. The data sources were original articles, reviews and consensus statements entered into the Medline and LILACS databases between 1997 and 2008. The following search terms were used: 'allergic rhinitis'; 'quality of life'; and 'sleep disorders'. Quality of life is often impaired in patients with allergic rhinitis, due to the classic symptoms of the disease (sneezing, pruritus, rhinorrhea and nasal obstruction). In addition, the pathophysiology of allergic rhinitis often disrupts sleep, leading to fatigue, irritability, memory deficits, daytime sleepiness and depression. The total burden of this disease goes beyond impairment of physical and social functioning. It has also a financial impact, which becomes greater when we consider the evidence that allergic rhinitis is a possible causal factor of comorbidities, such as asthma and sinusitis. Nasal obstruction, the most prominent symptom, is associated with sleep disorders, which can have a profound effect on mental health, learning, behavior and attention. Finally, allergic rhinitis-a chronic condition that affects adults, adolescents and children-is often underdiagnosed or inadequately treated. The deleterious impact that allergic rhinitis-related sleep disorders have on patient capacity to perform activities of daily living is an important component of the morbidity of the disease. With an accurate diagnosis, there are various available treatments that can reduce the burden of allergic rhinitis.
本次综述旨在展示变应性鼻炎与生活质量受损之间的关系的证据。数据来源为 1997 年至 2008 年间在 Medline 和 LILACS 数据库中收录的原始文章、综述和共识声明。使用了以下检索词:“变应性鼻炎”、“生活质量”和“睡眠障碍”。由于疾病的典型症状(打喷嚏、瘙痒、流涕和鼻塞),变应性鼻炎患者的生活质量通常会受损。此外,变应性鼻炎的病理生理学常常会扰乱睡眠,导致疲劳、易怒、记忆力减退、白天嗜睡和抑郁。这种疾病的总负担不仅仅局限于身体和社交功能的受损。它还具有经济影响,当我们考虑到变应性鼻炎可能是哮喘和鼻窦炎等合并症的一个潜在病因的证据时,这种影响就更大了。最突出的症状是鼻腔阻塞,与睡眠障碍有关,这可能对心理健康、学习、行为和注意力产生深远影响。最后,变应性鼻炎——一种影响成人、青少年和儿童的慢性疾病——常常被漏诊或治疗不足。与变应性鼻炎相关的睡眠障碍对患者日常生活活动能力的影响是该疾病发病率的一个重要组成部分。通过准确诊断,有多种可用的治疗方法可以减轻变应性鼻炎的负担。