Awan Muhammad Amer, Ramaesh Kanna
Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, Scotland.
J Pak Med Assoc. 2010 Feb;60(2):129-31.
Peripheral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma. PUK may occur in variety of systemic diseases including collagen vascular disease. We describe the outcome of superior forniceal advancement conjunctival pedicle (SFACP) in two patients with corneal perforation and impending perforation due to rheumatoid arthritis (RA) related auto immune corneal melt that has not previously been reported. Both patients had good recovery with restoration of vision when SFACP was performed as an adjunct to systemic immunosuppressive agents. SFACP is a valuable surgical option which may have an important role in reducing progression of corneal melt and underlying disease when used along with adequate systemic immunosuppressive agents.
周边溃疡性角膜炎（PUK）是一种由角膜缘角膜基质呈新月形破坏性炎症组成的病症。PUK可能发生在包括胶原血管病在内的多种全身性疾病中。我们描述了两例因类风湿性关节炎（RA）相关自身免疫性角膜溶解导致角膜穿孔和即将穿孔的患者接受上穹窿结膜蒂推进术（SFACP）的结果，此前尚未有相关报道。当SFACP作为全身免疫抑制剂的辅助治疗手段实施时，两名患者视力恢复良好。SFACP是一种有价值的手术选择，与适当的全身免疫抑制剂联合使用时，在减少角膜溶解进展和潜在疾病方面可能发挥重要作用。
