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结膜瓣手术治疗眼表疾病(综述)

Conjunctival flap surgery in the management of ocular surface disease (Review).

作者信息

Zemba Mihail, Stamate Alina-Cristina, Tataru Calin Petru, Branisteanu Daniel Constantin, Balta Florian

机构信息

Department of Ophthalmology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 050474, Romania.

Department of Ophthalmology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania.

出版信息

Exp Ther Med. 2020 Oct;20(4):3412-3416. doi: 10.3892/etm.2020.8964. Epub 2020 Jul 1.

Abstract

Literature regarding conjunctival flap surgery was reviewed to describe and discuss the rationale for this type of procedure. The conjunctival flap is an acknowledged surgery for the treatment of various corneal diseases with a chronically compromised ocular surface, such as severe dry eye, neurotrophic or neuroparalytic disease, or bullous keratopathy. The purpose of this surgery is to restore the integrity of the corneal surface and thus to prevent gradual corneal ulceration and secondary infection, as well as to ameliorate pain, reduce the need for frequent medications, improve cosmetic appearance, and offer an alternative to invasive surgery or enucleation. Since the introduction of more effective methods of treating severe ocular surface diseases, conjunctival flap surgery has rarely been the primary modality of treatment and has usually followed a range of medical and surgical treatments. The availability of improved ocular lubricants, more effective antimicrobials, bandage contact lenses, tissue adhesives, and other corneal and conjunctival surgical interventions, has reduced the need for conjunctival flaps. However, conjunctival flaps remain extremely useful in selected cases and deserve a place in the ophthalmologist's repertoire for the management of ocular surface disease.

摘要

对有关结膜瓣手术的文献进行了综述,以描述和讨论这种手术方式的基本原理。结膜瓣手术是一种公认的用于治疗各种眼表长期受损的角膜疾病的手术,如严重干眼症、神经营养性或神经麻痹性疾病,或大疱性角膜病变。该手术的目的是恢复角膜表面的完整性,从而防止角膜逐渐溃疡和继发感染,以及减轻疼痛、减少频繁用药的需求、改善外观,并提供一种替代侵入性手术或眼球摘除术的方法。自从引入了治疗严重眼表疾病的更有效方法以来,结膜瓣手术很少成为主要的治疗方式,通常是在一系列药物和手术治疗之后采用。改进的眼部润滑剂、更有效的抗菌药物、绷带式隐形眼镜、组织粘合剂以及其他角膜和结膜手术干预措施的出现,减少了对结膜瓣的需求。然而,结膜瓣在某些特定情况下仍然非常有用,在眼科医生治疗眼表疾病的方法中应占有一席之地。

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