Burmistrov M V, Ivanov A I, Petrov S V, Akhmetov T R, Sigal E I, Murav'ev V Iu, Moroshek A A, Broder I A
Vopr Onkol. 2009;55(6):712-6.
A protocol is suggested of complex diagnosis and treatment of Barrett's esophagus using sparing endoscopic removal of Barrett's epithelium in combination with surgery and medicinal antireflux therapy. Eighty-three patients were diagnosed and treated for hernia of esophageal foramen of the diaphragm and gastro-esophageal reflux complicated by Barrett's esophagus. Ninety-two percent of patients receiving our four-component treatment were cured; no recurrent esophageal adenocarcinoma was reported during the 56.7 +/- 2.4 month follow-up. Conversely, in patients receiving three-component treatment, efficacy was 56%; esophageal adenocarcinoma was reported in 3 (12%).
本文提出了一种巴雷特食管的综合诊断与治疗方案,该方案采用保留性内镜下切除巴雷特上皮,并结合手术及药物抗反流治疗。83例因食管裂孔疝和胃食管反流并发巴雷特食管而接受诊断和治疗的患者。接受我们四组分治疗的患者中有92%治愈;在56.7±2.4个月的随访期间未报告复发性食管腺癌。相反,接受三组分治疗的患者,有效率为56%;有3例(12%)报告发生食管腺癌。