Cevik Figen Caglan, Aykin Nevil, Naz Hasan
Department of Infectious Diseases and Clinical Microbiology, Yunus Emre General Hospital, Eskisehir, Turkey.
J Infect Dev Ctries. 2010 Mar 8;4(2):91-5. doi: 10.3855/jidc.572.
The study aimed to evaluate the complications and quality of the specimens of percutaneous liver biopsy in patients with chronic viral hepatitis who were scheduled for treatment and also to evaluate the contribution of the knowledge of ultrasound guided (USG) biopsy localization to the existing data.
Liver biopsies conducted at our clinic between 2003 and 2008 were retrospectively evaluated. In 53.8% of the cases, hepatobiliary USG was performed to mark the localization of the biopsy site. An automatically triggered Tru-Cut biopsy gun was used.
Biopsies were taken from the livers of 236 patients (46.6% male, 53.4% female) with a mean age of 47.1 +/- 12.5 years. The majority of patients had hepatitis C (61.9%); 1.6% experienced major complications (3 patient biliary peritonitis, 1 patient liver bleeding); 52.1% of the samples were > or = 1 cm in length; And 69.7% of the biopsy samples with specified portal area had > or = 4 portal areas. There was no statistically significant difference between the patients with localized and non-localized biopsy site in terms of major complications and length of biopsy samples ( respectively p = 1.000, p = 0.209 ).
We believe that percutaneous liver biopsy using Tru-Cut biopsy gun can be performed safely, with complications in 1.6% of the procedures. The length of the biopsy specimen is shorter than ideal values. Evaluation of the patients with and without USG-guided biopsy revealed no significant difference in terms of major complications and specimen size.
本研究旨在评估计划接受治疗的慢性病毒性肝炎患者经皮肝穿刺活检的并发症及标本质量，并评估超声引导（USG）活检定位知识对现有数据的贡献。
对2003年至2008年在我院进行的肝活检进行回顾性评估。53.8%的病例中，进行了肝胆USG以标记活检部位的定位。使用自动触发的Tru-Cut活检枪。
对236例患者（男性46.6%，女性53.4%）的肝脏进行了活检，平均年龄为47.1±12.5岁。大多数患者患有丙型肝炎（61.9%）；1.6%发生了严重并发症（3例患者发生胆汁性腹膜炎，1例患者发生肝出血）；52.1%的样本长度≥1cm；并且在指定门静脉区域的活检样本中，69.7%有≥4个门静脉区域。在严重并发症和活检样本长度方面，活检部位定位和未定位的患者之间没有统计学显著差异（分别为p = 1.000，p = 0.209）。
我们认为使用Tru-Cut活检枪进行经皮肝穿刺活检可以安全进行，1.6%的操作会出现并发症。活检标本的长度短于理想值。对有和没有USG引导活检的患者进行评估发现，在严重并发症和标本大小方面没有显著差异。
