切割针活检对口腔病变的组织学诊断：一项初步研究。

Histological diagnosis of oral lesions with cutting needle biopsy: a pilot study.

作者信息

Dos Santos José Antonio Rossi, Capella Diogo Lenzi, Rozza Rafaela Elvira, Ferreira Stefânia Jeronimo, Berti-Couto Soraya de Azambuja, Sant'ana-Filho Manoel, de Lima Antonio Adilson Soares, Westphalen Fernando Henrique, Couto-Souza Paulo Henrique

机构信息

Department of Stomatology, School of Dentistry, Pontifical Catholic University of Paraná Brazil.

Department of Stomatology, School of Dentistry, Pontifical Catholic University of Rio Grande do Sul Brazil.

出版信息

J Oral Maxillofac Res. 2011 Jul 1;2(2):e3. doi: 10.5037/jomr.2011.2203. eCollection 2011.

DOI:10.5037/jomr.2011.2203

PMID:24421990

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3886060/

Abstract

OBJECTIVES

The aim of this pilot study was to evaluate the effectiveness of cutting needle biopsy in the diagnosis of solid oral lesions.

MATERIAL AND METHODS

The biopsies were carried out on seven patients who presented with solid oral lesions with sizes ranging from 2 to 6 cm. Specimens were obtained from each lesion before conventional biopsies using a cutting needle with 18-gauge x 9 cm (MD TECH, Gainesville, FL, USA). A total of 64 specimens processed by hematoxylin-eosin staining method, were obtained. Afterwards, the analysis was performed by an oral pathologist, in two different stages, with and without the clinical history of each lesion. Then, these answers were compared with the final histological diagnosis.

RESULTS

Results presented by the descriptive analysis showed that the correct diagnosis using cutting needle biopsy without the clinical history of lesions was registered in 37.5% of cases, while with the clinical history in 76.6%.

CONCLUSIONS

Despite the promising results as a potential technique for biopsies and histological diagnosis of oral lesions, the cutting needle biopsy should be analyzed carefully in those cases.

摘要

目的

本初步研究的目的是评估切割针活检在口腔实性病变诊断中的有效性。

材料与方法

对7例出现大小为2至6厘米口腔实性病变的患者进行活检。在进行传统活检之前，使用18号×9厘米的切割针（美国佛罗里达州盖恩斯维尔市MD TECH公司）从每个病变处获取标本。共获得64个经苏木精-伊红染色法处理的标本。之后，由一名口腔病理学家分两个不同阶段进行分析，分别是有无每个病变的临床病史。然后，将这些结果与最终的组织学诊断进行比较。