老年恶性疾病结肠支架置入术的疗效和安全性。
Efficacy and safety of colonic stenting for malignant disease in the elderly.
机构信息
Department of Gastroenterology, Beaumont Hospital, Dublin, Ireland.
出版信息
Int J Colorectal Dis. 2010 Jun;25(6):747-50. doi: 10.1007/s00384-010-0917-6. Epub 2010 Mar 6.
BACKGROUND
Self-expandable metal stents (SEMS) are an accepted palliation for malignant colorectal obstruction. Outcomes of stent insertion solely in older patients are unknown.
OBJECTIVE
To compare outcomes of SEMS insertion for malignant colorectal disease, in older versus younger patients.
METHODS
Forty-three patients were retrospectively identified as having undergone SEMS insertion for obstructing colorectal cancer. Of these, 24 were > or = 70 years of age (older patient group) and 19 were <70 years of age (younger patient group).
RESULTS
There was no significant difference in successful SEMS insertion between the groups (88% in older versus 100% in younger patients, p > 0.05). Furthermore, the complication rate was similar in both groups (12.5% versus 26%, p > 0.10). There was no difference in median survival (113 days versus 135 days, p > 0.09).
CONCLUSION
Colorectal stenting for malignant disease in older patients is both safe and effective with comparative success and complication rates to a younger population.
背景
自膨式金属支架（SEMS）是治疗恶性结直肠梗阻的一种公认的姑息疗法。单独在老年患者中进行支架置入的结果尚不清楚。
目的
比较 SEMS 置入治疗老年和年轻患者恶性结直肠疾病的结果。
方法
回顾性确定了 43 例因阻塞性结直肠癌而行 SEMS 置入的患者。其中 24 例年龄≥70 岁（老年患者组），19 例年龄<70 岁（年轻患者组）。
结果
两组 SEMS 置入成功率无显著差异（老年组 88%，年轻组 100%，p>0.05）。此外，两组并发症发生率相似（12.5%对 26%，p>0.10）。中位生存期无差异（113 天对 135 天，p>0.09）。
结论
对于老年患者的恶性疾病，结直肠支架置入术既安全又有效，与年轻人群相比，成功率和并发症发生率相当。
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