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自膨式金属支架治疗急性恶性大肠梗阻

Management of acute malignant large-bowel obstruction with self-expanding metal stent.

作者信息

Mucci-Hennekinne S, Kervegant A G, Regenet N, Beaulieu A, Barbieux J P, Dehni N, Casa C, Arnaud J P

机构信息

Department of Visceral Surgery, CHU-Angers, 4 rue Larrey, Angers-49100, France.

出版信息

Surg Endosc. 2007 Jul;21(7):1101-3. doi: 10.1007/s00464-007-9258-0. Epub 2007 Mar 14.

Abstract

BACKGROUND

Colorectal stents are being used for palliation and as a "bridge to surgery" in obstructing colorectal carcinoma. The purpose of this study was to review our experience with self-expanding metal stents (SEMS) as the initial interventional approach in the management of acute malignant large bowel obstruction.

METHODS

Between February 2002 and May 2006, 67 patients underwent the insertion of a SEMS for an obstructing malignant lesion of the left-sided colon or rectum.

RESULTS

In 55 patients, the stents were placed for palliation, whereas in 12 they were placed as a bridge to surgery. Stent placement was technically successful in 92.5% (n = 62), with a clinical success rate of 88% (n = 59). Two perforations that occurred during stent placement we retreated by an emergency Hartmann operation. In intention-to-treat by stent, the peri-interventional mortality was 6% (4/67). Stent migration was reported in 3 cases (5%), and stent obstruction occurred in 8 cases (13.5%). Of the nine patients with stents successfully placed as a bridge to surgery, all underwent elective single-stage operations with no death or anastomotic complication.

CONCLUSIONS

Stent insertion provided an effective outcome in patients with malignant colonic obstruction as a palliative and preoperative therapy.

摘要

背景

结直肠支架正被用于缓解症状以及作为梗阻性结直肠癌的“手术桥梁”。本研究的目的是回顾我们使用自膨式金属支架(SEMS)作为急性恶性大肠梗阻初始介入治疗方法的经验。

方法

在2002年2月至2006年5月期间,67例患者因左侧结肠或直肠的梗阻性恶性病变接受了SEMS置入术。

结果

55例患者置入支架是为了缓解症状,而12例是作为手术桥梁。支架置入术在技术上成功的有92.5%(n = 62),临床成功率为88%(n = 59)。支架置入过程中发生的2例穿孔通过急诊Hartmann手术进行了处理。在意向性支架治疗中,围介入期死亡率为6%(4/67)。报告有3例(5%)发生支架移位,8例(13.5%)发生支架梗阻。在成功置入支架作为手术桥梁的9例患者中,所有患者均接受了择期一期手术,无死亡或吻合口并发症。

结论

支架置入术作为一种姑息性和术前治疗方法,在恶性结肠梗阻患者中取得了有效的治疗效果。

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